Thoracic duct embolization (TDE) is a percutaneous, image-guided occlusion of the TD. This technique was devised by one of the pioneers of Interventional Radiology, Dr Constantine Copez. Originally envisioned as a minimally invasive alternative to TD ligation, it is a 3-step process consisting of lymphangiography followed by percutaneous transabdominal catheterization of the CC and embolization of the TD proximal to the leak or occlusion. Embolization is most commonly a combination of coils and n-butyl cyanoacrylate (n-BCA) Lymphangiography historically was a time-consuming and technically challenging pedal cut down. There has been an update to the procedure with inguinal intranodal lymphangiography. This recent adaptation has made the procedure considerably shorter.In patients in whom percutaneous CC cannulation fails, the TD may be accessed from a retrograde approach from the subclavian vein.